Curcumin & Turmeric How It Works References

Turmeric and Joint health:Cell protection-helps to protect joints/helps to maintain joint flexibility /contributes to joint health.
Zeng, L. et al.(2021) The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis. Biosci Rep;41 (6):BSR20210817. The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis - PMC (nih.gov)
Curcumin helps to control inflammatory responses within the body.
Uddin SJ. et al. (2021). Curcumin and its Multi-target Function Against Pain and Inflammation: An Update of Pre-clinical Data. Curr Drug Targets;22(6):656-671. Curcumin and its Multi-target Function Against Pain and Inflammation: An Update of Pre-clinical Data - PubMed (nih.gov)
Mao Q.-Q. et al. (2019). Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe) Foods;8:185. Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe) - PMC (nih.gov)
Ginger root helps relieve the pains and aches associated with arthritis and associated conditions; May help alleviate and soothe pain associated with mobility issues.
Ballester P. et al. (2022). Effect of Ginger on Inflammatory Diseases. Molecules;27(21):7223. Effect of Ginger on Inflammatory Diseases - PMC (nih.gov)
Sharma S. et al. (2023). Revisiting the therapeutic potential of gingerols against different pharmacological activities. Naunyn Schmiedebergs Arch Pharmacol;396(4):633-647. Revisiting the therapeutic potential of gingerols against different pharmacological activities - PubMed (nih.gov)
Ginger root helps maintain immunity. Has significant antioxidant properties
Curcumin root helps to maintain the efficacy of the immune system. Has significant antioxidant properties.
Black pepper has significant antioxidant properties. Helps to maintain the integrity of the body by its antimicrobial and ani-parasitic effects and support for the immune system.
Deng T. et al. (2024) Immunomodulatory effects of curcumin on macrophage polarisation in rheumatoid arthritis. Front Pharmacol;15:1369337. Immunomodulatory effects of curcumin on macrophage polarisation in rheumatoid arthritis - PubMed (nih.gov)
Ginger root and Curcumin root have significant antioxidant properties.
Askari, G. et al (2020) The effects of ginger supplementation on biomarkers of inflammation and oxidative stress in adults: A systematic review and meta-analysis of randomised controlled trials. Journal of Herbal Medicine; 22: 100364. The effects of ginger supplementation on biomarkers of inflammation and oxidative stress in adults: A systematic review and meta-analysis of randomised controlled trials - ScienceDirect
Ashmita, G. et al. (2022)Effectiveness of Zingiber Officinale(ginger) compared with non-steroidal anti-inflammatory drugs and complementary therapy in primary dysmenorrhoea: A systematic review, Clinical Epidemiology and Global Health; 18:101152. Effectiveness of Zingiber Officinale(ginger) compared with non-steroidal anti-inflammatory drugs and complementary therapy in primary dysmenorrhoea: A systematic review - ScienceDirect
Kongsui R, Jittiwat J. (2024) In vivo protective effects of 6‑gingerol in cerebral ischemia involve preservation of antioxidant defences and activation of anti‑apoptotic pathways. Biomed Rep;20(6):85. In vivo protective effects of 6‑gingerol in cerebral ischemia involve preservation of antioxidant defences and activation of anti‑apoptotic pathways - PubMed (nih.gov)
Mohammad YA (2016) Gingerol and its role in chronic diseases. Adv Exp Med & Bio 929:177–207. 10.1007/978-3-319-41342-6_8. Gingerol and Its Role in Chronic Diseases - PubMed (nih.gov)
Ajayi BO, Adedara IA, Farombi EO.(2018) Protective mechanisms of 6-gingerol in dextran sulphate sodium-induced chronic ulcerative colitis in mice. Hum Exp Toxicol;37(10):1054-1068. Protective mechanisms of 6-gingerol in dextran sulphate sodium-induced chronic ulcerative colitis in mice - PubMed (nih.gov)
Curcumin root helps to keep the skin healthy and helps maintain the health of the liver.
Curcumin helps to maintain the health of the liver and contributes to support digestion.
Vaugh, A. Branum, A. and Sivamani, R. (2016) Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence.Phytotherapy Res ;30 (8): 1243-64. Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence - PubMed (nih.gov)
Heidari, H. et al. (2023) Curcumin-piperine co-supplementation and human health: A comprehensive review of pre-clinical and clinical studies. Phytotherapy research;37 (4): pg1462-1487. Phytotherapy Research | Medicinal Chemistry Journal | Wiley Online Library
Shoba, G. et al. (1998). Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med;64 (4) :353-6. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers - PubMed (nih.gov)
Suresh, D and Srinivasan, K. (2010)Tissue distribution & elimination of capsaicin, piperine & curcumin following oral intake in rats. Indian J Med Res.;131:682-91. Tissue distribution & elimination of capsaicin, piperine & curcumin following oral intake in rats - PubMed (nih.gov)

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