Magnesium Glycinate has become one of the most popular forms of magnesium supplements for good reason. Known for its calming properties and gentle effect on digestion, it’s often used to support sleep, reduce stress, and ease muscle tension. But is it right for you? In this article, we answer the most common questions about magnesium glycinate, including its benefits, side effects, and the best time to take it.
Magnesium glycinate is a highly bioavailable form of magnesium, meaning it's easily absorbed and used by the body. It’s made by combining magnesium with the amino acid glycine, which has naturally calming effects. When you take magnesium glycinate, it helps:
Because of its gentle effect on the gut, it’s a preferred choice for people who experience digestive issues with other forms of magnesium.
The benefits of magnesium glycinate extend beyond basic magnesium supplementation. Some of the most notable include:
These benefits make magnesium glycinate a go-to supplement for people dealing with stress, poor sleep, or muscle discomfort.

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Yes, magnesium glycinate and magnesium bisglycinate refer to the same compound. 'Bis' indicates that magnesium is bound to two glycine molecules. Both names are used interchangeably, and both offer the same absorption and benefits.
No, magnesium glycinate is not a sleeping pill, but it can improve sleep naturally. It calms the brain by supporting the production of GABA, a neurotransmitter that promotes relaxation. While it doesn’t cause sedation, it helps you fall asleep more easily and stay asleep longer.
Many people ask when to take magnesium glycinate for the best effect. You can take it at any time of day, but for sleep and relaxation, taking it 1–2 hours before bed is ideal. For daytime stress or muscle support, you might prefer to take it in the morning or early afternoon. It is usually better to take it with food to help with the absorption.
Most people tolerate magnesium glycinate very well. Side effects of magnesium glycinate are extremely rare but may include:
Taking it with food can help minimise any discomfort.
No. Magnesium glycinate does not cause weight gain. In fact, magnesium helps regulate insulin and may support healthy metabolism. If you notice weight changes, it’s likely related to other lifestyle or dietary factors.
No, magnesium glycinate does not cause constipation. In fact, other types of magnesium - like oxide - may have a laxative effect, but glycinate is known for being gentle on the digestive system.
No. Magnesium glycinate typically improves sleep, and it is sometimes used to help with insomnia. It also does not cause headaches - in fact, magnesium is often used to help prevent
migraines.
Magnesium glycinate is safe for most people; however, you should consult your doctor before taking it if you:
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